Lower-Division Courses
CHEM 101. The Science of Chemistry (3). General education introductory course. Teaches the basic concepts of chemistry that
will aid in understanding the physical world. No attempt to teach basic computational
or laboratory skills; instead emphasizes such concepts as atomic and molecular theory,
energy, structures, and theories regarding why reactions occur.
CHEM 103. Introductory Chemistry (5). 3R; 4L. General education introductory course. A survey of inorganic, organic, nuclear,
and biological chemistry. Recommended for the student who plans to take only one course
in chemistry. Students who expect to major in the natural sciences should take the
CHEM 211-212 sequence. Credit is not granted for both CHEM 103 and 211. Prerequisite:
one year of high school algebra or MATH 011.
CHEM 110. Preparatory Chemistry (3). A general chemistry course for students who have not had adequate preparation in
chemistry or physics. Enables students to improve their problem-solving skills and
to briefly review mathematics relevant to general chemistry. Introduces the basic
chemical concepts of atoms, molecules, chemical reactions, chemical equations, gas
laws, and solutions. Credit is allowed in only one of the following: CHEM 103, 110,
or 211. Prerequisites: one and a half units of high school algebra or MATH 011.
CHEM 211. General Chemistry I (5). 3R; 4L. General education introductory course. An introduction to the general concepts
of chemistry. Includes chemical stoichiometry, atomic and molecular structure, bonding,
gas laws, states of matter, and chemical periodicity. CHEM 211-212 meets the needs
of students who may wish to take more than one course in chemistry. Credit is allowed
in only one of the following: CHEM 211, 103, or 110. Prerequisites: a college-level
chemistry course such as CHEM 110, 101, or 103, or high school chemistry or physics;
and concurrent enrollment in MATH 111 or two units of high school algebra or MATH
011.
CHEM 212. General Chemistry II (5). 3R; 4L. General education further study course. Continuation of CHEM 211. Includes
thermodynamics, gaseous and ionic equilibria, kinetics, nuclear chemistry, electrochemistry,
qualitative analysis, and an introduction to theories of bonding. Prerequisite: CHEM
211 with a grade of C or better.
CHEM 301. Issues and Perspectives in Chemistry (3). Students explore the chemical concepts involved in a minimum of four current national
and international scientific, social, and economic issues, and analyze the complexity
of the possible solutions of these issues. Prerequisites: CHEM 101, 103, or 211
CHEM 481. Cooperative Education in Chemistry (1-4). Permits chemistry students to participate in the Cooperative Education program.
Offered Cr/NCr only. Courses for Graduate/Undergraduate Credit
Courses for Graduate/Undergraduate Credit
CHEM 514. Inorganic Chemistry (3). General education further study course. Basic inorganic chemistry emphasizing molecular
symmetry and structure, fundamental bonding concepts, ionic interactions, periodicity
of the elements, systematics of the chemistry of the elements, acid-base chemistry
and non-aqueous solvents, classical coordination chemistry, and introductory bioinorganic
chemistry. Prerequisite: CHEM 212 with a C or better.
CHEM 523. Analytical Chemistry (4). 2R; 6L. General education further study course. Evaluation of data, theory and application
of gravimetric analysis and precipitation, neutralization, and oxidation-reduction
volumetric analysis. Prerequisite: CHEM 212 with a C or better.
CHEM 524. Instrumental Methods of Chemical Analysis (4). 2R; 6L. Introduction to electroanalytical chemistry and optical method of analysis
and analysis and separation of complex mixtures, both inorganic and organic. Also
discusses basic computer programming as it applies to analytical chemistry. Prerequisite:
CHEM 523.
CHEM 531. Organic Chemistry I (5). 3R; 6L. General education further study course. An introduction to the study of
carbon compounds emphasizing reaction mechanisms, stereochemistry, and spectrographic
analysis. Prerequisite: CHEM 212 with a C or better.
CHEM 532. Organic Chemistry II (5). 3R; 6L. A continuation of CHEM 531 emphasizing the structure and reactions of principal
functional groups and compounds of biological interest. Prerequisite: CHEM 531 with
a grade of C or better.
CHEM 545. Physical Chemistry I (3). Focusing on macroscopic physical theories in chemistry and their relation to quantum
mechanics and statistical mechanics. Postulates of thermodynamics. The first law of
thermodynamics. Thermochemistry. Thermodynamic cycles. Entropy and the second law
of thermodynamics. Microscopic interpretation of entropy. The third law of thermodynamics.
Absolute entropies, Free energies. Standard states. Method of thermodynamic potentials.
Phase equilibria. Solution. Activity. Electrolyte solutions and Debye-Huckle theory.
Chemical equilibrium. Direction of reaction spontaneity. Equilibrium constants in
terms of standard free energies and partition functions. Reaction rate laws. Experimental
methods in chemical kinetics. Reaction mechanisms. Preequilibrium and steady state
approximation. Chain reactions. Catalysis. Gas-phase dynamics. Potential energy surfaces.
Transition state theory. Reaction kinetics in solution. Prerequisites: CHEM 212 with
a grade of C or better, one year of college physics, and MATH 344 or its equivalent.
CHEM 546. Physical Chemistry II (3). Kinetic theory, kinetics, transport phenomena, quantum theory, spectroscopy, and
statistical thermodynamics. Prerequisites: CHEM 545.
CHEM 547. Physical Chemistry Laboratory (2). 6L. Physical chemistry experiments that illustrate principles learned in CHEM 546
and 548. Prerequisite or co-requisite: CHEM 546.
CHEM 605. Medicinal Chemistry (3). For students interested in chemistry related to the design, development, and mode
of action of drugs. Course describes those organic substances used as medicinal agents
and explains the mode of action and chemical reactions of drugs in the body; illustrates
the importance and relevance of chemical reactions as a basis of pharmacological activity,
drug toxicity, allergic reactions, carcinogenicity, etc; and brings about a better
understanding of drugs. Includes transport, basic receptor theory, metabolic transformation
of drugs, discussion of physical and chemical properties in relation to biological
activity, drug design, structure-activity relationships, and discussion of a select
number of organic medicinal agents. Prerequisites: CHEM 532 or equivalent; a semester
of biochemistry (CHEM 661 or 662) and a year of biology are strongly recommended.
CHEM 615. Advanced Inorganic Chemistry (3). Includes modern bonding theories, structure and spectra of inorganic compounds,
coordination and organometallic chemistry, boranes, inorganic ring systems and polymers,
inorganic environmental chemistry, mechanisms of inorganic reactions, and solid state
chemistry. Prerequisites CHEM 514, Corequisite CHEM 546.
CHEM 616. Inorganic Chemistry Laboratory (2). 6L. Experimental methods of inorganic chemistry. Prerequisite or co-requisite: CHEM
615.
CHEM 661. Introductory Biochemistry (3). General education further study course. An introductory course for chemistry majors
including chemistry/business majors and students in life sciences. Not recommended
for the BS in chemistry for health sciences or biochemistry field majors for whom
CHEM 662 and 663 are required. Introduces thermodynamics and biological oxidation-reduction
reactions; structure, metabolism, and synthesis of proteins, carbohydrates, lipids,
and nucleic acids; enzyme kinetics, photosynthesis, and transfer of genetic information.
Prerequisite: CHEM 532.
CHEM 662. Biochemistry I (3). Study of major constituents of the cell: protein, carbohydrate, glycoprotein, lipid,
nucleic acid, nucleoprotein; enzyme catalysis; biological oxidations; photosynthesis;
and introduction to intermediary metabolism. A fundamental background of biology or
microbiology is recommended but not essential. Prerequisites: CHEM 523 and 532 or
equivalents.
CHEM 663. Biochemistry II (3). Study of metabolism and control of carbohydrates, lipids, phosphoglycerides, spingolipids,
sterols, amino acids and proteins; synthesis of porphyrins, amides and polyamines;
synthesis and metabolism of purines, pyrimidines, and nucleotides; synthesis and structure
of DNAs, RNAs and proteins; organization and functioning of genes; evolution of proteins
and nucleic acids; hereditary disorders of metabolism; biochemistry of endocrine glands;
major nutrients and vitamins; body fluids and generalized tissues. A fundamental background
of biology or microbiology is recommended but not essential. Prerequisite: CHEM 662.
CHEM 664. Biochemistry Laboratory (3). 1R; 6L. Practical training in biochemical procedures and literature searching; experiments
include isolation, characterization and assay of biomolecules and use of centrifugation,
chromatography, electrophoresis, spectrophotometry, enzyme kinetics, and radioactive
labeling techniques. Should be taken concurrently with CHEM 662 or CHEM 663. Prerequisite:
CHEM 532 or equivalent.
CHEM 666. Special Topics in Biochemistry (3). (Offered fall semester in even-numbered years.) Discusses a small number of current
problems in biochemistry in depth. Requires reading of published research in the field.
Prerequisites: BIOL 211 and CHEM 662 and 663.
CHEM 669. Research in Biochemistry (2). Cross-listed as BIOL 669. S/U grade only. Students in the biochemistry field major
participate in a biochemistry research project under the direction of a faculty member.
Requires a written report summarizing the results. May be repeated once for credit.
Prerequisites: BIOL 420 and CHEM 662 or 663 and 664.
CHEM 690. Independent Study and Research (2-3). Studies performed must be directed by a faculty member in the Department of Chemistry.
Repeatable for credit. Amaximum LIBERAL ARTS AND SCIENCES 141 of 3 credit hours may
be counted toward graduation. Prerequisite: departmental consent.
CHEM 700. Chemistry Seminar (1). S/U grade only. Students give seminars on either papers recently published in the
literature or on their own research. Repeatable for credit.
CHEM 701. Chemistry Colloquium (1). S/U grade only. Speakers for the colloquium consist of outstanding chemists from
other institutions and faculty. Repeatable for credit.
CHEM 709. Special Topics in Chemistry (2-3). A discussion of topics of a special significance and interest to faculty and students.
Offerings announced in advance. Repeatable for credit.
CHEM 712. Coordination Chemistry (3). The study of the synthesis, characterization, and properties of coordination compounds.
Includes nomenclature, fundamental bonding concepts, principles of synthesis, mechanisms
of substitution and electron transfer reactions, catalysis, and solid-state phenomena.
Prerequisite: CHEM 615 or equivalent.
CHEM 713. Physical Methods in Inorganic Chemistry (3). An introduction to electronic and vibrational spectroscopy, magnetic susceptibility,
EPR, NMR, Mossbauer spectroscopy, and X-ray crystallography as applied to inorganic
systems. Emphasis on interpretation of results for understanding the electronic and
molecular structure of compounds.
CHEM 715. Advanced Spectroscopy I (3). An introduction to 1H and 13C NMR spectroscopy including basic concepts such as
integration, chemical shifts, diamagnetic shielding, magnetic anisotropy, spin-spin
coupling (first and second-order), coupling constants, proton decoupled 13C NMR interpretation
of 1H and 13C NMR spectra. More advanced topics include NOE and protein structural
mapping, and multidimensional techniques such as COSY, DEPT, INEPT, molecular motion
by NMR, coupling to I>0 metal centers, including those with <100 percent natural abundance,
virtual coupling in metal complexes, NMR of paramagnetic systems and use of paramagnetic
shift reagents. An introduction to mass spectroscopy including instrumentation—magnetic
sector, quadrupole, ion trap, MS-MS; sample preparation and interfaces—GC-MS, LC-MS,
electrospray, MALDI; methods of ionization—electron impact, chemical ionization, electrospray,
interpretation of mass spectra—basic concepts, fragmentation patterns. An introduction
to the interpretation of mid-infrared spectroscopy of complex molecules and ionic
compounds followed by the synthesis of results from NMR, MS and mid IR spectra to
determine structure. Emphasis on interpretation of results for understanding electronic
and molecular properties of chemical compounds related to their symmetry.
CHEM 717. Advanced Spectroscopy II (3). An introduction to electronic and vibrational spectroscopy, EPR and magnetic properties
of compounds. A study of the electric field interaction of radiation, electronic and
vibrational spectroscopy, and the magnetic field interaction of radiation, EPR and
magnetism, with molecular systems examining the different changes in state that molecules
can undergo. Emphasis on interpretation of results for understanding electronic and
molecular properties of chemical compounds related to their symmetry and structure.
CHEM 719. Modern Synthetic Methods (3). An introduction to modern synthetic methods in chemistry. A detailed investigation
of the synthetic chemistry of anions is followed by a detailed survey of functional
group interconversions, then oxidation and reduction reactions. The topic of retrosynthetic
analysis is introduced. Topics in inorganic synthesis include organometallic bond
forming and breaking reactions, ligand synthesis and replacement, solid state synthesis,
and topics in bioinorganic synthesis.
CHEM 721. Advanced Biochemistry (3). An introduction to advanced biochemical concepts, processes, and techniques. A comprehensive
survey of structure functions of biomolecules including proteins, nucleic acids, lipids
and carbohydrates is carried out. Protein synthesis, DNA replication and translation,
biological membrane and membrane transport are covered. Enzyme mechanisms and kinetics
and protein structure/function are discussed in detail. Biochemical, molecular biological,
biophysical, and chemical techniques that are commonly used in the study of biochemical
processes are introduced and discussed.
CHEM 722. Advanced Physical Chemistry (3). An indepth overview of the fundamentals of thermodynamics, kinetics, quantum mechanics
and statistical mechanics as they apply to chemistry. Special emphasis is placed on
solution thermodynamics, kinetics of coupled reactions, statistical mechanics of macromolecules
and quantum mechanics as it applies to spectroscopy. Prerequisites: CHEM 546, and
547, or the equivalent undergraduate courses in physical chemistry.
CHEM 731. Physical Organic Chemistry (3). Discussion of advanced topics in stereochemistry and conformational analysis and
organic reaction mechanisms. Prerequisite:CHEM 532.
CHEM 732. Advanced Organic Synthesis (3). Discussion of modern synthetic methods in organic chemistry, including carbon-carbon
forming reactions, oxidation and reduction reactions, protective groups, and organometallic
chemistry. Prerequisite: CHEM 532.
CHEM 734. Instrumental Methods for Research (3). Designed to prepare graduate students or other researchers to perform spectroscopy
experiments relevant to their research. The identity of organic compounds can be determined
by the information provided by several types of spectra: mass, infrared, nuclear magnetic
resonance, fluorescence, and ultraviolet. Students learn to operate such instruments
as the Varian 2200 GC/MS mass spectrometer, the ThermoNicolet Avatar FTIR spectrophotometer,
the Varian Mercury 300 and Inova 400 NMR spectrometers, the Fluorolog fluorescence
spectrophotometer and the Hitachi U-2010 and Varian Cary 100 UV-Vis spectrophotometers
in the department’s NMR and analytical facilities. The focus of this class is technique
and not the interpretation of spectra. On successful completion of this course, students
are authorized to use departmental instruments. Prerequisite: departmental consent.
CHEM 738. Structure Determination and Spectral Analysis of Organic Compounds (3). Discusses chiroptical techniques, infrared, ultraviolet, nuclear magnetic and electron
spin resonance and mass spectroscopy, and their practical utilization in structure
determination. Prerequisite: CHEM 532.
CHEM 741. Quantum Chemistry (3). Theoretical basis of atomic and molecular structure. Includes the postulates of
quantum mechanics, exact solutions for the particle-in-a-box and the hydrogen atom,
variation and perturbation techniques, electron spin, Hartree-Fock and configuration-interaction
methods, molecular orbital and valence-bond wave functions, and virial and Helimann-Feynman
theorems. Prerequisites: CHEM 546, MATH 344 or equivalent. Co-requisite: CHEM 705
or equivalent.
CHEM 744. Computational Quantum Chemistry (3). An introduction to molecular orbital procedures and methods for calculating a wide
range of physical, chemical, and electronic properties of systems large enough to
be of interest to inorganic, organic, and biochemists. Using commercial molecular
orbital software programs such as MOPAC, SPARTAN, and GAUSSIAN, students learn to
select appropriate "model" computational procedures to predict properties of molecules
and reactions. By comparison with experiment, students learn to assess the range of
applicability and accuracy of the "model" methods as applied to various categories
of chemical systems. Properties considered include energies and structures of molecules,
ions, and transition states; vibrational frequencies, IE and RAMAN spectra; Thermochemical
properties, heat of formation, bond and reaction energies, isomerization energy barriers;
reaction pathways; molecular orbitals, atomic charges, dipole and multipole moments,
ionization potentials, bond orders; orbital energies and photoelectron spectroscopy;
excited state properties, singlet and triplet surfaces. Prerequisite: CHEM 546 or
equivalent (MATH 344 is necessary.)
Courses for Graduate Students Only
CHEM 809. Special Studies in Chemistry. (2-3). Systematic study in selected areas of chemistry. Repeatable for credit. Course content
differs from one offering to the next.
CHEM 814. Organometallic Chemistry. (3). A study of the synthesis, structure, bonding, reactivity and industrial applications
of organotransition and nontransition metal compounds. Prerequisite: Chem. 615 or
equivalent.
CHEM 815. Bioinorganic Chemistry. (3). The study of the role of inorganic chemistry in biological systems. Includes electron
transport, biological catalysis mediated by metal ions, metal storage and transport,
ion transport and the role of transition metals in metabolism. Prerequisites: Chem.
615 and 663 or equivalents.
CHEM 822. Analytical Separations. (3). The theory and practice of analytical separation methods including gas and liquid
chromatography, ion exchange and electrophoresis. Prerequisite: Chem. 524 or equivalent.
CHEM 823. Analytical Spectroscopy. (3). Absorption (UV visible, IR and atomic); emission: flame emission and atomic absorption
spectrometry, molecular fluorescence and phosphorescence methods; Raman, nuclear magnetic
resonance and electron spin resonance spectroscopy; X-ray methods. Lectures and discussions
on theory and practice. Particular emphasis on instrumentation and the acquisition
of artifact-free data. Prerequisite: Chem. 524 or equivalent.
CHEM 824. Electro analytical Chemistry. (3). Includes voltammetry, polarography, chromoamperometry and coulometry; reversible
and irreversible diffusion controlled processes; CE (chemical reaction before electrical
reaction), EC (electrical reaction before chemical reaction) and catalytic reaction;
and organic polarography and voltammetry. Prerequisite: Chem. 524 or equivalent.
CHEM 831. Advanced Physical Organic Chemistry. (3). Includes molecular orbital theory, sigma tropic rearrangements, electrocyclic reactions,
cycloadditions, reactive intermediates and photochemistry. Prerequisite: Chem. 731.
CHEM 832. Modern Synthetic Methods. (3). Discussion of retrosynthetic analysis, applications, asymmetric syntheses and stereo-chemistry.
Prerequisite: Chem. 732.
CHEM 834. Heterocyclic Chemistry. (3). An account of the physical and chemical properties of the main classes of heterocyclic
compounds. Prerequisite: Chem. 732.
CHEM 835. Bioorganic Chemistry. (3). Includes the chemistry of amino acids and peptides, enzyme structure and function
and inhibitor design. Prerequisites: Chem. 662, 663 and 732 or 662 and concurrent
enrollment in 663 and 732.
CHEM 841. Advanced Quantum Chemistry. (3). Considers advanced applications of quantum mechanics to atomic and molecular problems.
Includes determinant wave-functions, angular momentum coupling, time-dependent perturbation
theory, relativity considerations, tensor operators and molecular orbital calculations.
Prerequisites: Chem. 705 and 741 or equivalents.
CHEM 842. Chemical Kinetics. (3). A description of reacting systems, including the mathematical and experimental characteristics
of simple and complex kinetic systems. Discusses the theories of chemical kinetics,
as well as the kinetics of homogeneous reactions in the gas phase, the kinetic aspects
of solution reactions, heterogeneous reactions and selected topics of current interest.
Prerequisite: Chem. 546 or equivalent.
CHEM 843. Statistical Thermodynamics. (3). Develops Boltzmann, Fermi-Dirac and Boise-Einstein statistical mechanics with applications
to gaseous-state and solid-state chemical problems. Emphasizes the relationship of
statistical mechanics and thermodynamics. Considers applications of statistical thermodynamics
to polymers. Prerequisites: Chem. 546, 845 or equivalents.
CHEM 845. Chemical Thermodynamics. (3). A presentation of the basic three laws of thermodynamics in a classical framework
to increase understanding of real physical systems. Emphasizes theory and its application
to chemical systems. Prerequisites: Chem. 545, 546 and Math. 344 or equivalents.
CHEM 846. Molecular Spectroscopy. (3). The theoretical basis for spectroscopy and spectroscopic determinations of molecular
structure. Includes polyelectronic atoms, time-dependent perturbation theory, vibration
and rotation of diatomic molecules, vibration and rotation of polyatomic molecules,
electronic spectra and magnetic resonance spectroscopy. Prerequisites: Chem. 741 or
its equivalent and Chem. 705 or its equivalent.
CHEM 861. Enzyme Mechanisms. (3). An introduction to the study of enzyme mechanisms. Modern approaches include steady-state,
relaxation and chemical modification methods. Prerequisite: Chem. 662 or 663 or equivalent.
CHEM 863. Analytical Biochemistry. (3). A review of modern analytical methods used in biochemistry and molecular biology
including absorbance and fluorescence spectroscopy chromatography (affinity, gel-filtration,
HPLC, ion-exchange, ion-pair), gel electrophoresis, radioactive tracer methods; cloning,
sequencing and recombinant DNA procedures. Prerequisites: Biol. 203 and 204 and Chem.
662 or 663 or equivalents.
CHEM 864. Nucleic Acids: Structure, Chemistry and Function. (3). A comprehensive examination of the structure and conformation of DNA, RNA, and their
components. Studies reactivity and modification of nucleotides and polynucleotides
for different chemicals and mutagens. Reviews chemical synthesis of polynucleotides
and sequence analysis of nucleic acids, including site-specific mutagenesis. Studies
nucleic acid functions and information transfer in biochemical systems. Also studies
major nucleases and discusses DNA-protein interactions.
CHEM 890. Research in Chemistry. (2-12). S/U grade only. Research for the student planning to receive an MS. Research is
directed by a faculty member. Repeatable for credit.
CHEM 990. Research in Chemistry. (2-16). S/U grade only. Research for the student planning to receive the PhD. Research is
directed by a faculty member. Repeatable for credit.